AM-2233

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AM2233 is a full agonist of the central cannabinoid (CB1) receptor (Ki = 2.8 nM). Most of the affinity towards the CB1 receptor resides within the (R)-enantiomer of AM2233.

Which exhibits a Ki value of 0.2 nM and has ~8-fold higher affinity for CB1 compared to WIN 55,212-2 (Ki = 1.6 nM).1 AM2233 was developed for use as a selective radiology for mapping the distribution of the CB1 receptor in the brain.

Recently, however, AM2233 has received attention as a cannibalistic acquired for recreational use as a replacement for restricted substances. This compound is intended for forensic and research applications.

AM2233 N-(3-chloropentyl) isomer is a synthetic cannabinoid which differs from AM2233. By having a 3-chloro group rather than a 5-fluoro group on the pentyl chain. The physiological and toxicological properties of this compound are not established. This product is for forensic and research applications.